The Isle of Wight circular route is a long-standing favourite with cyclists, and at 65 miles it makes an enjoyable, leisurely weekend route.
We'd recommend you ride this route clockwise so that the sea's always on your left. The views from the Isle of Wight coast roads are every bit as good as you'd expect, and this route is an attractive circumnavigation which manages to avoid the worst of the traffic.
That said, there are a few locations where heavy traffic is unavoidable, particularly in the east of the island towards Bembridge. The route bypasses the towns of Ryde, Sandown and Shanklin, but you could modify your ride to take them in – particularly to enjoy the excellent railway paths through the latter.
Access from the mainland is easy via the ferries from Portsmouth and Southampton.