This is a lovely section to cycle overall. Aside from the simple navigation the peace and quiet was lovely. Plenty of narrowboats to look at, a few canoeists were out and plenty of folk out for a leisurely walk.
The going is generally good, though it had been dry before my trip along - what's it like in a wet winter is unknown to me! I was fully loaded with four panniers and just about comfortable to put my bike through the route. Some of the path is narrow, many many tree routes and 5 and 6 inch rises to get onto some of the bridges. This isn't a route for your best road bike, you need something that can roll with the terrain.
Newbury is a decent stop off point for a break, plenty of shops and cafes a minute or so from the canal. Highly recommend the Bara Brith at Aldermaston tea shop!
As you get towards Reading the path was a little littered but seen far worse.